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Updated: Aug 10, 2026

Isolation and Characterization of Neutrophils with Anti-Tumor Properties
Published on: June 19, 2015
CE: Febrile Neutropenia in the Chemotherapy Patient
Anne Marie Foley1, Megan Hoffman
1Anne Marie Foley is a clinical nurse specialist at the Memorial Sloan Kettering Cancer Center (MSKCC) in New York City. Megan Hoffman is a nurse leader at the David H. Koch Center for Cancer Care at MSKCC; at the time of this writing, she was a clinical nurse specialist at MSKCC. Contact author: Anne Marie Foley, foleya1@mskcc.org . The authors and planners have disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
Febrile neutropenia is a serious complication of chemotherapy treatment and may present as the only clinical sign of infection. If not addressed in a timely manner, it may progress to multisystem organ failure and may be fatal. Initial assessment of fever in those receiving chemotherapy requires prompt administration of antibiotics, ideally within one hour of presentation. Depending on the clinical status of the patient, antibiotic treatment may occur in the inpatient or outpatient setting. Nurses play an important role in the identification and treatment of patients at high risk for febrile neutropenia through assessment and adherence to clinical practice guidelines. In addition, nurses play an active role in patient education regarding risk factors, protective measures, and signs and symptoms of infection in the immunocompromised oncology patient.
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