Related Experiment Video
Updated: Aug 4, 2025

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
Published on: November 29, 2024
[Subtyping of type 2 diabetes: an approach towards personalized treatment]
Johan Huizing1, Bruce H R Wolffenbuttel2,3
1Onderzoeksbureau Johan Huizing, Roden.
Abstract:
Several research groups have attempted to describe the heterogeneity of type 2 diabetes by creating specific subtypes. A Swedish study evaluating subtypes of type 2 diabetes soon after diagnosis has proposed the existence of 5 clusters. Subtyping can lead to a better understanding of the underlying pathophysiology, better prediction of the development of diabetes-related complications, and a personalized approach towards lifestyle interventions and prescription of glucose-lowering medication. In addition to subtyping, there is increasing interest in the various factors which predict the glycaemic response of an individual to a specific medication. Hopefully, these developments will in the near future lead to a better-individualized treatment of people with type 2 diabetes.
Related Concept Videos
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Diabetes: Symptoms, Diagnosis, and Complications
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...

