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Related Experiment Videos

[The hypersensitive respiratory system in childhood].

D Berdel

    Klinische Padiatrie
    |March 1, 1986
    PubMed
    Summary

    Increased bronchial mucosal permeability, from various stimuli, is the most likely cause of bronchial hyperreactivity and childhood asthma. Inhalative provocation tests help diagnose this condition.

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    Allergy·2018

    Area of Science:

    • Pulmonology
    • Allergy and Immunology
    • Pediatric Respiratory Medicine

    Context:

    • Bronchial hyperreactivity is a key feature in asthma.
    • Understanding its aetiology is crucial for effective management.
    • Childhood asthma bronchiale presents unique challenges.

    Purpose:

    • To discuss the aetiological factors and mechanisms of bronchial hyperreactivity.
    • To emphasize the role of increased bronchial mucosal permeability.
    • To outline the use of inhalative provocation tests.

    Summary:

    • The study highlights increased bronchial mucosal permeability, induced by endogenous or exogenous stimuli, as the primary explanation for bronchial hyperreactivity.
    • This permeability is strongly linked to the development of childhood asthma bronchiale.
    • The abstract also covers the indications, contraindications, and interpretation of unspecific inhalative provocation tests.

    Impact:

    • Provides a clearer understanding of bronchial hyperreactivity mechanisms in pediatric asthma.
    • Informs diagnostic strategies using bronchial provocation tests.
    • Contributes to the aetiological knowledge base for asthma research.

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