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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
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Expanding and explaining symptoms in knee osteoarthritis trajectories: fluctuations, flares, and future directions

M J Thomas1

  • 1Centre for Musculoskeletal Health Research, School of Medicine, Keele University, Staffordshire, ST5 5BG, UK; Haywood Academic Rheumatology Centre, Midlands Partnership University NHS Foundation Trust, Haywood Hospital, Staffordshire ST6 7AG, UK.

Osteoarthritis and Cartilage
|April 6, 2023
PubMed
Abstract

No abstract available in PubMed .

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The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
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The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
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