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Wireless High-Frequency Peripheral Nerve Stimulation for Chronic Refractory Knee Pain Post-total Knee Replacement
Gaurav Chauhan1, Suresh K Srinivasan2, Suchit Khanduja3
1Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center Presbyterian, Pittsburgh, USA.
Cureus
|April 7, 2023
Summary
Joint replacement surgeries are increasing, leading to more cases of chronic knee pain. Peripheral nerve stimulation offers an effective solution for persistent pain after knee replacement surgery.
Area of Science:
- Orthopedics
- Pain Management
- Neuromodulation
Background:
- The global geriatric population is expanding, driving an increase in joint replacement surgeries, particularly total knee replacements.
- Chronic pain following total knee replacement (TKR) is a prevalent issue, impacting patient recovery and quality of life.
Observation:
- While most post-TKR pain cases resolve with conservative treatments like physical therapy and medication, a subset of patients experiences refractory pain.
- This persistent pain can significantly hinder functional recovery and patient satisfaction.
Findings:
- Peripheral nerve stimulation (PNS), a form of neuromodulation, has emerged as a viable therapeutic option for managing chronic, unremitting pain after TKR.
- PNS targets specific peripheral nerves to modulate pain signals, offering an alternative when conventional methods fail.
Implications:
- PNS represents a promising advancement in the management of challenging post-surgical knee pain.
- This neuromodulation technique could improve outcomes for patients with refractory pain, reducing long-term disability and enhancing overall quality of life.

