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Autologous serum eye drops in dry eye disease: Preferred practice pattern guidelines.
Jayesh Vazirani1, Uma Sridhar2, Nikhil Gokhale3
1Center for Excellence in Cornea and Ocular Surface Disorders, Excel Eye Care, Ahmedabad, Gujarat, India.
Indian Journal of Ophthalmology
|April 7, 2023
Summary
Autologous serum eye drops lubricate and heal the ocular surface, offering a valuable treatment for dry eye disease and other ocular surface disorders. This review simplifies preparation and use guidelines for these effective eye drops.
Area of Science:
- Ophthalmology
- Regenerative Medicine
Background:
- Autologous serum eye drops (ASEDS) are established treatments for ocular surface disorders.
- Existing literature shows significant variability in ASEDS preparation, concentration, and usage protocols.
Framework:
- This review synthesizes current evidence and expertise to provide simplified, standardized recommendations.
- Focuses on practical aspects: preparation, transport, storage, and administration of ASEDS.
Implementation:
- Provides clear guidelines for consistent and effective preparation of autologous serum.
- Outlines best practices for storage and transport to maintain serum integrity.
- Offers recommendations for optimal usage duration and frequency.
Implications:
- Aims to reduce variability in ASEDS preparation and application, improving treatment consistency.
- Supports the effective management of dry eye disease, persistent epithelial defects, and neurotrophic keratopathy.
- Enhances the therapeutic potential of autologous serum for ocular surface regeneration.
