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Updated: Aug 3, 2025
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A Unified Methodological Framework for Vestibular Schwannoma Research
Published on: June 20, 2017
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SRS for Vestibular Schwannomas - Current Status.
Sanjeev Pattankar1, Paurush Pasricha1, Basant K Misra1
1Department of Neurosurgery and Gamma Knife, P D Hinduja Hospital and MRC, Mumbai, Maharashtra, India.
Neurology India
|April 7, 2023
Summary
Stereotactic radiosurgery (SRS) offers excellent tumor control for vestibular schwannomas (VS), with minimal risks. Further research is needed to predict hearing preservation and compare SRS techniques.
Area of Science:
- Neurosurgery
- Radiation Oncology
Background:
- Vestibular schwannomas (VS) are tumors requiring effective treatment.
- Stereotactic radiosurgery (SRS) is an established treatment modality for VS.
Approach:
- Comprehensive literature review on SRS safety and efficacy in VS.
- Analysis of clinical experience with SRS (N=294) and post-SRS microsurgery.
- Evaluation of GammaKnife SRS outcomes in sporadic and NF2-related VS cohorts.
Key Points:
- SRS demonstrates high local tumor control (>95% at 5 years) for small-to-medium VS.
- Adverse radiation effects are minimal; hearing preservation rates vary.
- Our GammaKnife cohort showed 95.5% (sporadic) and 93.8% (NF2) tumor control.
Conclusions:
- SRS is a reliable alternative for VS management.
- Microsurgery in post-SRS VS is challenging, necessitating near-total excision for optimal outcomes.
- Further studies should focus on predicting hearing preservation and comparing SRS modalities.
