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A Study of Factors Influencing Delayed Diagnosis in Pediatric Cancers: A Step Towards Better Outcomes-A
Abhilasha Sampagar1, Sarapu Keerthana2, Merle Casia Dias2
1Department of Medical Oncology.
Insights
Delayed diagnosis significantly impacts pediatric cancer survival in India. Factors like younger age, parental illiteracy, and low income contribute to longer delays, highlighting the need for increased awareness and accessible care.
Area of Science:
- Oncology
- Public Health
- Pediatrics
Background:
- India accounts for 20% of global pediatric cancer diagnoses annually.
- Survival rates for childhood cancers in India lag behind developed nations, primarily due to diagnostic delays.
Purpose of the Study:
- To investigate factors contributing to delayed diagnosis in pediatric cancer patients in India.
- To identify patient-related and socioeconomic factors influencing diagnostic delays to inform intervention strategies.
Main Methods:
- A cross-sectional study involving 185 children diagnosed with malignancy at a tertiary care hospital.
- Diagnosis delay was categorized into patient delay and physician delay.
- Statistical analyses included descriptive statistics, Mann-Whitney U test, Kruskal-Wallis test, and multivariate linear regression.
Main Results:
- The median diagnosis delay was 59 days (patient delay: 30 days, physician delay: 7 days).
- Younger children, those with illiterate parents, and from low-income families experienced significantly longer diagnosis delays.
- Children initially seen by general practitioners had longer delays compared to those seen by pediatricians.
Conclusions:
- Augmenting parental awareness and improving attitudes towards seeking medical care are crucial.
- Decentralizing specialized pediatric oncology services to rural areas can reduce mortality from curable childhood cancers.
Abstract:
Annually, India contributes to one-fifth of newly diagnosed pediatric cancers worldwide. Poor outcome in India as compared with developed nations is mainly attributed to delayed diagnosis and study of factors influencing delay in diagnosis holds paramount importance in formulating strategies and counter-measures to improve survival. It was a cross-sectional study conducted on children diagnosed with malignancy at a tertiary care hospital. Diagnosis delay was defined and further divided into patient delay and physician delay. Various patient-related factors and socioeconomic factors that could affect diagnosis were studied. Statistical analysis included descriptive analysis, Mann-Whitney U test, Kruskal-Wallis test, and multivariate linear regression. Of 185 patients enrolled, median diagnosis delay, patient delay, and physician delays were 59, 30, and 7 days respectively. Median diagnosis delay was significantly higher in younger children, children of illiterate parents, and low income. Median diagnosis delay in children presenting to a general practitioner (9 [4 to 29] days) was higher than those presenting to a pediatrician (5.5 [2 to 18] days). Sex, occupation of parents, and distance from oncology center did not affect time for diagnosis. We concluded that augmentation of the parent's attitudes, increased awareness, and decentralization of specialized pediatric care to rural areas can significantly reduce mortality from, otherwise, curable malignancies.
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