Restoring musculocutaneous nerve function in 146 brachial plexus operations - A retrospective analysis
Gregor Durner1, Alexandra Gerst2, Ina Ulrich2
1Peripheral Nerve Surgery Unit, Department of Neurosurgery, University of Ulm, Lindenallee 2, 89312 Günzburg, Germany.
Clinical Neurology and Neurosurgery
|April 7, 2023
Summary
Surgical reconstruction of the musculocutaneous nerve after brachial plexus injury yields significant functional recovery, with nerve transfers and autologous repairs showing comparable outcomes. Younger patient age is a key predictor of successful elbow flexion restoration.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Reconstructive Surgery
Background:
- Brachial plexus lesions, often caused by trauma, severely impact upper extremity function, particularly elbow flexion.
- Restoring elbow flexion is critical for functional recovery and independence in affected individuals.
Purpose of the Study:
- To compare the outcomes of different surgical methods for musculocutaneous nerve reconstruction following brachial plexus injury.
- To identify predictors of successful functional recovery after these procedures.
Main Methods:
- Retrospective analysis of 146 brachial plexus surgeries involving musculocutaneous reconstruction (2013-2017).
- Evaluation of demographic data, surgical techniques, nerve characteristics, BMI, and functional outcomes (MRC strength grades).
- Multivariate analysis using SPSS to determine significant predictors of outcome.
Main Results:
- Oberlin reconstruction was the most frequent procedure.
- Nerve transfer and autologous repair demonstrated similar functional outcomes.
- No significant difference in outcome was observed between nerve transfers with or without nerve grafts.
- Younger patient age was identified as a strong predictor of better outcomes.
- Longer nerve graft length (>15 cm) and higher BMI (>25) were associated with inferior results.
Conclusions:
- Musculocutaneous nerve reconstruction leads to substantial clinical improvement in brachial plexus injuries.
- Nerve transfer and autologous reconstruction are equally effective.
- Younger age is an independent predictor of superior clinical outcomes.
- Further prospective multicenter studies are warranted to validate these findings.


