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[Varicella and herpes zoster].

H Spiess

    Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
    |March 1, 1986
    PubMed
    Summary

    Chickenpox and shingles are caused by the same virus. Vaccination is recommended for women planning pregnancy and immunocompromised individuals to prevent serious complications.

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    Area of Science:

    • Virology
    • Immunology

    Context:

    • Chickenpox (varicella) and shingles (herpes zoster) are caused by the same virus, identified in 1958.
    • The virus establishes lifelong immunity but can reactivate, particularly in older adults or those on immunosuppressive therapy.

    Purpose:

    • To review the epidemiology, clinical manifestations, and vaccination recommendations for varicella-zoster virus (VZV).
    • To highlight the risks of VZV infection during pregnancy and in immunocompromised individuals.

    Summary:

    • VZV causes chickenpox and shingles, with reactivation leading to herpes zoster.
    • Approximately 7% of women of childbearing age lack VZV antibodies.
    • Pregnancy can result in abortion or severe congenital defects if VZV infection occurs.

    Impact:

    • Varicella vaccination is crucial for women planning pregnancy to prevent congenital abnormalities.
    • Vaccination is also recommended for immunocompromised patients and healthcare personnel in high-risk settings.
    • Early identification and vaccination strategies are essential for public health management of VZV.

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