Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deep learning-enabled ultra-widefield retinal vessel segmentation with an automated quality-optimized angiographic phase selection tool.

Eye (London, England)·2021
Same author

Mandible Biomechanics and Continuously Erupting Teeth: A New Defect Model for Studying Load-Bearing Biomaterials.

Biomedicines·2021
Same author

miR-467 regulates inflammation and blood insulin and glucose.

Journal of cellular and molecular medicine·2021
Same author

Automated Quality Assessment and Image Selection of Ultra-Widefield Fluorescein Angiography Images through Deep Learning.

Translational vision science & technology·2020
Same author

Bioabsorbable Versus Titanium Screws in Anterior Cruciate Ligament Reconstruction Using Hamstring Autograft: A Prospective, Randomized Controlled Trial With 13-Year Follow-up.

The American journal of sports medicine·2020
Same author

Comparative Effectiveness of Tumor Response Assessment Methods: Standard of Care Versus Computer-Assisted Response Evaluation.

JCO clinical cancer informatics·2019
Same journal

Clinical Application of a Modified Ureteral Stent Placement Technique in Ureteroscopy.

Surgical innovation·2026
Same journal

Vibe Coding in Neurosurgery: Bridging the Gap Between Clinical Needs and Digital Innovation-A Narrative Review and Practical Perspective.

Surgical innovation·2026
Same journal

Screw-Lock: A Novel Technique to Secure Burr Hole Base Ring in DBS Surgery.

Surgical innovation·2026
Same journal

Preliminary in Vitro Study on an RFID-Tagged Gauze Detection System to Prevent Retention During Laparoscopic Procedures.

Surgical innovation·2026
Same journal

Feasibility of Three-Dimensional Imaging in Accurately Assessing the Peritoneal Cancer Index for Peritoneal Carcinomatosis.

Surgical innovation·2026
Same journal

Laparoscopic Vs Open Ladd's Procedure for Intestinal Malrotation in Infants and Children: A Systematic Review and Meta-Analysis.

Surgical innovation·2026
See all related articles

Related Experiment Video

Updated: Aug 3, 2025

Performing Microscope-Mounted Y-Shaped Cutting Tests
06:15

Performing Microscope-Mounted Y-Shaped Cutting Tests

Published on: January 20, 2023

1.9K

Evaluating Performance of Circular Staplers Using Comparative Test Methods for Evidence-Based Surgery.

Haley Strassner1, Alexander Caulk1, Nicholas Reher1

  • 1Surgical Innovations, Medtronic plc, North Haven, CT, USA.

Surgical Innovation
|April 8, 2023
PubMed
Summary
This summary is machine-generated.

Triple-row staplers showed higher leak pressure and staple line perfusion compared to double-row staplers. Novel preclinical testing methods were developed to assess surgical stapling technology advancements.

Keywords:
anastomosisanastomotic leakcircular staplerevidence-based medicineperfusionstaple line security

More Related Videos

A Training and Testing System for Performing Vascular Reconstruction In Vitro
09:52

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Published on: October 26, 2019

8.0K
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

585

Related Experiment Videos

Last Updated: Aug 3, 2025

Performing Microscope-Mounted Y-Shaped Cutting Tests
06:15

Performing Microscope-Mounted Y-Shaped Cutting Tests

Published on: January 20, 2023

1.9K
A Training and Testing System for Performing Vascular Reconstruction In Vitro
09:52

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Published on: October 26, 2019

8.0K
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

585

Area of Science:

  • Surgical innovation
  • Biomedical engineering
  • Medical device testing

Background:

  • Anastomotic leak is a significant postoperative concern in circular stapler surgery.
  • Variability in testing methods hinders the assessment and comparison of new surgical stapling technologies.
  • Robust preclinical test methods are essential for advancing stapling device technology.

Purpose of the Study:

  • To develop and validate novel, reproducible preclinical test methods for evaluating surgical staplers.
  • To compare the performance of triple-row (TriEEA) and double-row (ECP) circular staplers using these new methods.

Main Methods:

  • Quantified leak pressure, staple line perfusion, staple line security, and device removal force.
  • In vivo testing for leak and perfusion; synthetic medium testing with Instron for removal force and security.
  • Statistical analysis using unpaired student's t-test or Kruskal-Wallis test (P < .05).

Main Results:

  • Triple-row staplers (TriEEA) exhibited 73% higher leak pressure than double-row staplers (ECP).
  • TriEEA showed significantly higher staple line perfusion (148%) and required 78% less force for device removal.
  • However, TriEEA staple line failure force was lower than ECP at specific pressures.

Conclusions:

  • The study presents novel, reproducible methodologies for assessing surgical stapler performance.
  • These methods enhance clinical relevance and facilitate direct comparisons between different stapling devices.
  • The findings demonstrate the utility of the new test methods in evaluating key design features of triple-row versus double-row staplers.