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Published on: March 18, 2020
Laryngeal Anatomy, Molecular Biology, Cause, and Risk Factors for Laryngeal Cancer
Anthony B Law1, Nicole C Schmitt1
1Department of Otolaryngology - Head and Neck Surgery, Emory University School of Medicine, 550 Peachtree Street Northeast, 11th Floor Otolaryngology, Atlanta, GA 30308, USA; Winship Cancer Institute, Emory University School of Medicine, 550 Peachtree Street Northeast, 11th Floor Otolaryngology, Atlanta, GA 30308, USA.
Abstract:
Laryngeal cancer is declining in incidence in many parts of the world, as smoking becomes a less common habit. However, challenging cases of laryngeal cancer still exist and require expertise from otolaryngologists. This article reviews the relevant anatomy and lymphatic drainage pathways of the larynx because they pertain to cancer spread. The molecular and immune landscapes of laryngeal cancer, which are tightly linked to smoking, are also discussed.
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