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18F-FDG PET/CT in Waldenström associated amyloidosis
Lynn De Mey1, Sim Vermeulen, Sophie Bourgeois
1Department of Nuclear Medicine, Universitair Ziekenhuis Brussel, Laarbeeklaan 101-103, 1090 Brussels, Belgium. frank.degeeter@gmail.com.
Abstract:
Amyloidoisis in patients with Waldenström macroglobulinemia (WM) mostly involves the heart, peripheral nerves and kidneys. Retroperitoneal amyloidosis is a rare finding. We describe a 62-year-old man with an incidental finding of a monoclonal gammopathy and elevated inflammatory parameters. Bilateral moderately active retroperitoneal infiltration with punctiform calcifications was found on fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging. Taken together, these findings are suggestive of Waldenström associated amyloidosis. Computed tomography-guided retroperitoneal biopsy confirmed the diagnosis.
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