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[Pineocytoma--a case report].

T Hattori, J Shinoda, H Kondo

    No Shinkei Geka. Neurological Surgery
    |March 1, 1986
    PubMed
    Summary
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    This report details a rare pineocytoma case in a young woman. Initial treatment relieved symptoms, but the tumor recurred, necessitating further surgical intervention and adjuvant therapy.

    Area of Science:

    • Neuro-oncology
    • Neurosurgery
    • Pathology

    Background:

    • Pineocytomas are rare tumors originating from pineal parenchymal cells.
    • Obstructive hydrocephalus is a common complication of pineal region tumors.

    Observation:

    • A 27-year-old woman presented with headaches and nausea due to a non-enhancing pineal mass causing obstructive hydrocephalus.
    • Initial ventriculoperitoneal (VP) shunting provided symptomatic relief.
    • Histopathology revealed a tumor resembling normal pineal gland tissue with rosette formation.

    Findings:

    • The pineocytoma showed resistance to combined chemo-radiotherapy, with tumor progression and ring enhancement on CT scans.
    • Recurrence led to a second partial resection via a different surgical approach.

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  • Clinical deterioration included blurred vision and Parinaud's sign.

    • Implications:

    • This case highlights the challenges in managing recurrent pineocytomas, even after multimodal therapy.
    • The study underscores the importance of considering surgical re-intervention for progressive pineal region tumors.
    • Further research into optimal treatment strategies for rare pineal tumors is warranted.