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[Radiosensitive meningioma--report of a case]
No Shinkei Geka. Neurological Surgery
|March 1, 1986
Summary
A young male with a large sphenoid ridge meningioma experienced symptom relief and tumor reduction after radiotherapy. Successful surgical removal was achieved following radiation therapy, demonstrating its efficacy for this type of brain tumor.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Neuroradiology
Background:
- A 24-year-old male presented with generalized convulsive seizures, papilledema, and visual field defects.
- Radiological imaging revealed a large, hypervascular meningioma in the left sphenoid ridge and sellar region.
Observation:
- The tumor exhibited characteristics of an angioblastic meningioma, hemangiopericytoma type, deemed difficult for complete surgical resection due to size and vascularity.
- Initial Cobalt-60 radiotherapy (49 Gy) resulted in significant tumor volume reduction and symptom improvement.
Findings:
- High radiosensitivity was observed during treatment, with tumor volume decreasing to one-third post-irradiation.
- The patient experienced resolution of headache and memory disturbance following radiotherapy.
Implications:
- This case highlights the radiosensitivity and potential for successful surgical debulking after neoadjuvant radiotherapy for large, complex meningiomas.
- Radiotherapy can be an effective strategy to manage challenging meningiomas, improving surgical outcomes and patient prognosis.