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Updated: Aug 3, 2025

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
Use of honey in diabetic foot ulcer: Systematic review and meta-analysis
Ebru Yildiz Karadeniz1, Emine Kaplan Serin2
1Mersin University Faculty of Nursing, Department of Fundamentals of Nursing, Mersin, Turkey.
Objective:
The aim of this study was to evaluate the role of honey dressing as an effective intervention for diabetic foot wound management and to provide a reliable basis for future clinical study.
Materials And Methods:
We analyzed an assortment of randomized controlled trial (RCT), quasi-experimental and cross-sectional studies. We selected RCTs and quasi-experimental studies for meta-analysis. We only conducted a descriptive analysis for observational studies.
Results:
The meta-analysis showed that honey used effectively reduces wound recovery time and rate, incurred pain, hospital stay, and accelerates granulation in DFU wounds.
Conclusions:
Our findings suggest that honey effectively promotes healing in DFU. Further research is needed to elucidate these findings so that this form of treatment can be widely applied.
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