Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Auditory Pathway01:15

Auditory Pathway

5.5K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Altered EEG markers of reward learning during abstinence in alcohol dependence: A probabilistic reversal learning study.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Physiologically Based Pharmacokinetic Modelling of Hydroxyurea in Patients with Sickle Cell Disease: A Special Focus on Lactating Women and Breastfed Infants to Inform Safe Dosing and Breastfeeding Strategies.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Ramadan fasting for patients with chronic respiratory diseases: a systematic review and consensus recommendations for healthcare professionals.

ERJ open research·2025
Same author

The evolving landscape of digital inhaler platforms and adherence support in chronic airways disease.

Chronic respiratory disease·2025
Same author

Digital remote maintenance inhaler adherence interventions in COPD: a systematic review and meta-analysis.

European respiratory review : an official journal of the European Respiratory Society·2024
Same author

Can we measure whether asthma guidelines lead to improved care?

NPJ primary care respiratory medicine·2024

Related Experiment Video

Updated: Aug 3, 2025

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

10.3K

Adaptive cueing strategy for gait modification: A case study using auditory cues.

Tina L Y Wu1, Anna Murphy2, Chao Chen3

  • 1Department of Electrical and Computer Systems Engineering, Monash University, Clayton, VIC, Australia.

Frontiers in Neurorobotics
|April 10, 2023
PubMed
Summary

This study shows a novel closed-loop cueing framework effectively improves gait in people with Parkinson's (PwP). The human-in-the-loop system demonstrated superior efficiency and robustness compared to other cueing strategies.

Keywords:
Parkinson's diseasecontinuum carehuman-in-the-looprehabilitation roboticswearable robotics

More Related Videos

Postural Organization of Gait Initiation for Biomechanical Analysis Using Force Platform Recordings
06:21

Postural Organization of Gait Initiation for Biomechanical Analysis Using Force Platform Recordings

Published on: July 26, 2022

2.6K
A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance
07:19

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

Published on: March 19, 2020

6.0K

Related Experiment Videos

Last Updated: Aug 3, 2025

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

10.3K
Postural Organization of Gait Initiation for Biomechanical Analysis Using Force Platform Recordings
06:21

Postural Organization of Gait Initiation for Biomechanical Analysis Using Force Platform Recordings

Published on: July 26, 2022

2.6K
A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance
07:19

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

Published on: March 19, 2020

6.0K

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Rehabilitation Science

Background:

  • Parkinson's disease frequently causes gait impairments, impacting mobility and quality of life.
  • Cue training, using external stimuli (visual, auditory, haptic), is a known strategy to improve gait in people with Parkinson's (PwP).
  • Closed-loop cueing strategies, which adapt in real-time, show potential for overcoming cue dependency but are under-explored in PwP.

Purpose of the Study:

  • To assess the feasibility of a novel human-in-the-loop closed-loop cueing framework for PwP.
  • To evaluate the framework's ability to modify gait cadence (speed up/slow down) in early-stage Parkinson's.
  • To compare the framework's performance against fixed and proportional cueing strategies.

Main Methods:

  • Adaptation of a human-in-the-loop framework to create an individualized gait cueing model.
  • Preliminary feasibility study involving four participants with early-stage Parkinson's disease.
  • Comparison of the novel framework against fixed and proportional cueing approaches for cadence modification.

Main Results:

  • The target cadence significantly influenced gait performance.
  • The proposed closed-loop framework and fixed cueing approaches showed similar effectiveness in slowing cadence.
  • The novel framework exhibited superior efficiency, explainability, and robustness across participants.
  • Participants demonstrated the highest retention of gait improvements without cues when using the proposed framework.
  • The proportional cueing approach did not show clear benefits over other methods.

Conclusions:

  • The human-in-the-loop closed-loop cueing framework is a feasible and promising approach for gait rehabilitation in PwP.
  • This adaptive cueing strategy offers advantages in efficiency, explainability, and robustness compared to traditional methods.
  • Further research is warranted to explore the long-term efficacy and broader applicability of this novel framework for Parkinson's gait disorders.