Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genetic counseling for teratogen exposure.

C R King

    Obstetrics and Gynecology
    |June 1, 1986
    PubMed
    Summary

    Comprehensive genetic counseling is crucial for teratogen-exposed pregnancies. Considering all risk factors, including family history and multiple exposures, significantly alters counseling outcomes and supports informed decisions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Principles and Techniques of Expert Laparoscopic Surgical Dissection.

    Journal of minimally invasive gynecology·2016
    Same author

    A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans.

    Clinical pharmacology and therapeutics·2010
    Same author

    Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy.

    Journal of thrombosis and haemostasis : JTH·2009
    Same author

    Preparation, structure, and stability of Pt and Pd monolayer modified Pd and Pt electrocatalysts.

    Physical chemistry chemical physics : PCCP·2009
    Same author

    Combination of human tumor necrosis factor-alpha (hTNF-alpha) gene delivery with gemcitabine is effective in models of pancreatic cancer.

    Cancer gene therapy·2009
    Same author

    A 61-year-old man with pain in antecubital fossa after an elbow hyperextension injury.

    British journal of sports medicine·2009

    Area of Science:

    • Medical Genetics
    • Reproductive Toxicology
    • Prenatal Counseling

    Background:

    • Teratogen exposure poses risks to pregnancy.
    • Genetic counseling is essential for evaluating these risks.
    • Multiple risk factors can complicate prenatal decision-making.

    Purpose of the Study:

    • To evaluate the impact of comprehensive genetic counseling on teratogen-exposed patients.
    • To assess the influence of multiple risk factors on counseling outcomes.
    • To determine pregnancy outcomes following detailed genetic risk assessment.

    Main Methods:

    • Retrospective analysis of 200 patients referred for genetic counseling post-teratogen exposure.
    • Evaluation of risk factors including family history, advanced maternal age, and multiple teratogen exposures.
    • Assessment of changes in genetic counseling based on comprehensive risk evaluation.

    Main Results:

    • 52% of patients had exposure to multiple teratogenic agents.
    • One-third had a positive family history of genetic disease; 10% were of advanced maternal age.
    • Comprehensive counseling, considering all risk factors, altered recommendations for the majority of patients.
    • 97% of patients continued their pregnancies after complete counseling.
    • Pregnancy terminations were primarily linked to documented human teratogen exposure.

    Conclusions:

    • Thorough genetic counseling is vital for accurate risk assessment in teratogen-exposed pregnancies.
    • Integrating multiple risk factors leads to more complete and effective counseling.
    • Comprehensive counseling empowers patients to make informed decisions, maximizing successful pregnancy outcomes.

    Related Experiment Videos