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Vaccination coverage in children with juvenile idiopathic arthritis, inflammatory bowel diseases, and healthy peers:

Elizaveta Makarova1, Aygul Khabirova2, Natalia Volkova3

  • 1Department of Polyclinic Pediatrics, Saint-Petersburg State Pediatric Medical University, Saint-Petersburg 194100, Russia.

World Journal of Clinical Pediatrics
|April 10, 2023
PubMed

Insights

Children with juvenile idiopathic arthritis (JIA) and inflammatory bowel disease (IBD) have lower vaccine coverage. Physician encouragement and clear communication are crucial for improving vaccination rates in these vulnerable pediatric populations.

Area of Science:

  • Pediatric Rheumatology
  • Pediatric Gastroenterology
  • Immunology
  • Public Health

Background:

  • Children with immune-mediated diseases like juvenile idiopathic arthritis (JIA) and inflammatory bowel disease (IBD) face increased infection risk.
  • This heightened risk stems from disease-related immune dysfunction and the use of immunosuppressive medications.

Purpose of the Study:

  • To assess and compare vaccine coverage in children with IBD and JIA against that of healthy children.
  • To identify factors influencing vaccination rates in these pediatric patient groups.

Main Methods:

  • A cross-sectional study utilizing an electronic online questionnaire survey.
  • Data collected from legal representatives of 190 children: 81 with JIA, 51 with IBD, and 58 healthy controls (HC).

Main Results:

  • Patients with JIA and IBD exhibited lower vaccine coverage compared to healthy children.
  • Medical conditions were the primary reason for incomplete vaccinations in JIA and IBD patients.
  • Physician encouragement for vaccination was lowest in JIA patients, impacting coverage.

Conclusions:

  • Pediatric patients with JIA and IBD demonstrate suboptimal vaccine coverage.
  • Effective physician communication and personalized vaccination strategies are essential for improving coverage in chronically ill children.
  • Current vaccination promotion approaches for healthy children may not be optimal for immune-mediated disease populations.
Abstract

Keywords:
Immune-mediated diseasesInflammatory bowel diseasesJuvenile idiopathic arthritisVaccine coverageVaccines

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