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Updated: Aug 3, 2025

Deciphering the Structural Effects of Activating EGFR Somatic Mutations with Molecular Dynamics Simulation
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EGFR endocytosis: more than meets the eye

Aysegul Sapmaz, Ayse Elif Erson-Bensan

    Oncotarget
    |April 10, 2023
    PubMed
    Summary

    Endocytosis regulates protein fate after receptor activation, impacting cancer. This review focuses on the EGF-SNX3-EGFR pathway and its role in deregulated epidermal growth factor receptor (EGFR) endocytosis in breast cancer.

    Keywords:
    EGFRSNX3USP32endocytosis

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