Return emergency department visits for recurrent pulmonary embolism symptoms in children and adolescents

Dana Egan-Sherry1, Philip Grosse2, James D Cooper1

  • 1Department of Pediatrics, Division of Hematology/Oncology/Bone Marrow Transplant, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA.

Blood Advances
|April 10, 2023
PubMed

Insights

Pulmonary embolism (PE) in children often leads to return visits for related symptoms, with increased age and female sex as risk factors. Recurrence is rare when patients maintain appropriate anticoagulation.

Area of Science:

  • Pediatric Medicine
  • Cardiology
  • Radiology

Background:

  • Pediatric pulmonary embolism (PE) rates have risen significantly over 20 years.
  • Outcomes post-hospitalization for pediatric PE are not well-understood.
  • Many children experience persistent symptoms like chest pain or dyspnea after PE diagnosis.

Purpose of the Study:

  • To assess emergency department (ED) return rates for PE-related symptoms in children.
  • To evaluate the diagnostic utility of repeat computed tomography angiography (CTA) in pediatric PE patients.
  • To identify risk factors for ED return visits and PE recurrence.

Main Methods:

  • Retrospective cohort study of 96 pediatric patients diagnosed with PE.
  • Analysis of return visits to the ED for PE-related symptoms.
  • Review of repeat computed tomography angiography (CTA) utilization and outcomes.

Main Results:

  • 42% of patients returned to the ED for PE-related symptoms, with a median return time of 34 days.
  • Repeat CTAs were frequently performed (74 total), averaging 1.8 per returning patient.
  • Increased age and female sex were identified as risk factors for ED return visits; PE recurrence was 8% and linked to thrombotic risk factors.

Conclusions:

  • Pediatric PE patients frequently return to the ED for related symptoms, often necessitating repeat imaging.
  • Risk factors for return visits include older age and female sex.
  • Developing risk stratification for PE recurrence can help optimize follow-up care and reduce unnecessary imaging.

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