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Updated: Aug 3, 2025

Studying Copper Nanoparticle-Induced Programmed Cell Death in Bacteria

Studying Copper Nanoparticle-Induced Programmed Cell Death in Bacteria

Published on: May 16, 2025

Copper-based nanoparticles against microbial infections.

Xiumin Li^1,2, Yalin Cong^2,3, Muhammad Ovais³

¹Department of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, Liaoning, China.

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology

|April 10, 2023

Summary

This summary is machine-generated.

Copper-based nanoparticles show promise for fighting drug-resistant bacteria and viruses. This review covers their functionalization, antimicrobial activity, applications, and safety, guiding future nanomedicine development for infectious diseases.

Keywords:

antimicrobial activity bacteria copper-based nanoparticles microbial infection virus

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Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

Area of Science:

Nanomedicine
Infectious Disease Therapeutics
Materials Science

Background:

Antimicrobial resistance and viral threats pose significant global health challenges.
Novel strategies are urgently needed to combat these evolving health risks.
Copper-based nanoparticles (CBNPs) are emerging as potent antimicrobial agents.

Purpose of the Study:

To review the functionalization of copper-based nanoparticles.
To elucidate the antibacterial and antiviral activities and applications of CBNPs.
To discuss the toxicity, biodistribution, and persistence of CBNPs.

Main Methods:

Literature review of studies on copper-based nanoparticles.
Analysis of functionalization strategies for enhanced antimicrobial efficacy.
Synthesis of information on CBNP applications in combating infectious agents.

Main Results:

CBNPs demonstrate broad-spectrum antimicrobial activity against bacteria and viruses.
Functionalization enhances the efficacy and targeting of CBNPs.
Review covers key aspects including toxicity and biodistribution.

Conclusions:

Copper-based nanoparticles offer a promising platform for developing new antimicrobial therapies.
Further research into functionalization and safety is crucial for clinical translation.
This review provides a guide for designing advanced nanomaterials for infectious disease management.