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Related Concept Videos

Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

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A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion
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Autonomic dysfunction and exercise intolerance in concussion: a scoping review.

Ryan Pelo1, Erin Suttman2, Peter C Fino3

  • 1Department of Physical Therapy and Athletic Training, University of Utah, 520 Wakara Way, Salt Lake City, UT, 84108, USA. ryan.pelo@hsc.utah.edu.

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
|April 10, 2023
PubMed
Summary
This summary is machine-generated.

Concussion often causes exercise intolerance due to autonomic dysfunction. Further research is needed to understand the specific mechanisms linking autonomic impairment to symptoms and recovery after mild traumatic brain injury.

Keywords:
Autonomic nervous systemCardiovascular controlExerciseMild traumatic brain injury

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Area of Science:

  • Neurology
  • Sports Medicine
  • Physiology

Background:

  • Concussion frequently leads to exercise intolerance, hindering return to activities.
  • Altered cardiovascular autonomic regulation is a suspected contributor to post-concussive exercise intolerance.
  • Understanding these mechanisms can guide rehabilitation strategies.

Purpose of the Study:

  • To systematically review and synthesize existing research on the link between exercise intolerance and autonomic dysfunction following concussion.
  • To identify common themes and knowledge gaps in the current evidence base.

Main Methods:

  • A systematic review following PRISMA guidelines was conducted.
  • Studies involving mild traumatic brain injury (mTBI)/concussion with both autonomic and exercise intolerance testing were included.
  • Exclusion criteria addressed confounding neurological conditions and non-human studies.

Main Results:

  • 17 studies were included from an initial screening of 3116 publications.
  • Significant variability in testing protocols and inclusion criteria limited cross-study comparisons.
  • The reviewed literature supports the role of autonomic dysfunction in exercise intolerance post-concussion.

Conclusions:

  • Autonomic dysfunction is a key factor in exercise intolerance after concussion.
  • Specific mechanisms of impairment and their relationship to symptom recovery require further investigation.
  • More standardized research approaches are needed.