Sensitivity of Schizophrenia Endophenotype Biomarkers to Anticholinergic Medication Burden

Yash B Joshi¹, Juan L Molina¹, David L Braff¹+16

• ¹Desert Pacific Mental Illness Research Education and Clinical Center, VA San Diego Healthcare System (Joshi, Molina, Braff, Sprock, Swerdlow, Light); Department of Psychiatry, University of California, San Diego (Joshi, Molina, Braff, Greenwood, Sprock, M. Tsuang, Swerdlow, Light); Department of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles (Green, Neuchterlein); Desert Pacific Mental Illness Research Education and Clinical Center, VA Greater Los Angeles Healthcare System, Los Angeles (Green, Sugar); Department of Psychiatry, University of Pennsylvania, Philadelphia (Ruben C. Gur, Raquel E. Gur, Turetsky); Department of Psychiatry, Harvard Medical School, Boston (Stone); Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston (Stone); Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford (Lazzeroni); Department of Biomedical Data Science, Stanford University, Stanford (Lazzeroni); Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle (Radant, D. Tsuang); Northwest Geriatric Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle (D. Tsuang); Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York (Silverman); Research & Development, James J. Peters VA Medical Center, New York (Silverman); Department of Biostatistics, UCLA School of Public Health, Los Angeles (Sugar).