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Bone-specific physical activity questionnaire-derived skeletal loading score predicts bone geometry, density, and
Benjamin K Weeks1,2, Amy T Harding3, Steven L Watson3,4
1School of Health Sciences and Social Work, Griffith University, Gold Coast Campus, Southport, Queensland, Australia. b.weeks@griffith.edu.au.
Journal of Bone and Mineral Metabolism
|April 11, 2023
Summary
Physical activity history, measured by the bone-specific physical activity questionnaire (BPAQ), is linked to bone strength indices. This suggests BPAQ captures relevant bone loading history for adaptive stimuli.
Area of Science:
- Bone health and physical activity research.
- Skeletal biomechanics and osteology.
Background:
- The bone-specific physical activity questionnaire (BPAQ) assesses physical activity relevant to bone health based on mechanical loads throughout life.
- Understanding the relationship between lifelong physical activity and bone strength is crucial for skeletal health.
Purpose of the Study:
- To investigate the association between historical bone-relevant physical activity and bone strength parameters derived from peripheral quantitative computed tomography (pQCT).
Main Methods:
- Recruited 532 healthy volunteers (ages 4-97).
- Assessed bone density, area, and strength indices of the tibia and radius using pQCT.
- Determined past bone-specific physical activity (pBPAQ) scores from birth.
- Utilized Pearson correlation analysis to examine relationships.
Main Results:
- pBPAQ scores showed significant associations with bone density at specific tibial and radial sites (r=0.145-0.261, p<0.05).
- Associations were found between pBPAQ scores and total bone area at tibial and radial sites (r=0.129-0.156, p<0.05).
- pBPAQ scores correlated with bone strength indices across all measured sites (r=0.123-0.234, p<0.05).
Conclusions:
- Historical bone-relevant physical activity, as measured by pBPAQ, is independently associated with pQCT-derived bone strength indices.
- The BPAQ appears to effectively capture bone loading history relevant for skeletal adaptation.
- Further research with larger sample sizes is recommended to explore the influence of age on these relationships.
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