Related Experiment Video
Updated: Aug 3, 2025

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
World's first en bloc heart-lung transplantation using the paragonix lungguard donor preservation system
Daniel Neto1, Brandon Guenthart1, Yasuhiro Shudo1
1Department of Cardiothoracic Surgery, Center for Academic Medicine, Stanford University School of Medicine, 453 Quarry Road, Stanford, CA, 94305, USA.
Abstract:
We present the first en bloc heart-lung donor transplant procurement using the Paragonix LUNGguard™ donor preservation system. This system offers reliable static hypothermic conditions designed to prevent major complications such as cold ischemic injury, uneven cooling and physical damage. While this represents a single case, the encouraging results warrant further investigation.

