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Effectiveness of the systemic immune inflammation index to predict atrial fibrillation recurrence after cryoablation

Elmas Kaplan1, Firdevs A Ekızler1, Halenur Saribaş1

  • 1Department of Cardiology, University of Health Sciences, Ankara City Hospital, Ankara, 06800, Turkey.

Biomarkers in Medicine
|April 12, 2023
PubMed

Background: We aimed to investigate the predictive role of systemic immune inflammation index (SII) on atrial fibrillation (AF) recurrence following cryoballoon-based AF ablation. Materials & methods: A total of 370 consecutive patients with symptomatic AF who underwent cryoablation were enrolled. The patients were divided into two groups according to recurrence development. Results: During the follow-up period of 25.0 ± 6.7 months, recurrence was observed in 77 patients (20.8%). Receiver operating characteristic analysis demonstrated that using a cutoff level of 532, SII had a sensitivity of 71% and specificity of 68%. In the multivariate Cox model, high SII was a significant predictor of the recurrence. Conclusion: This study showed that higher SII level is an independent predictor of AF recurrence.

Keywords:
atrial fibrillationbiomarkercryoballoon ablationinflammationrecurrencesystemic immune inflammation index

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