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A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
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A versatile artificial skin platform for sweat sensor development.

Emma J M Moonen1,2, Tanveer Ul Islam1,2, Sebastiaan van Kemenade1

  • 1Microsystems, Department of Mechanical Engineering, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands. j.m.j.d.toonder@tue.nl.

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Summary
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A novel artificial skin platform mimics human skin

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Area of Science:

  • Biomedical Engineering
  • Materials Science

Background:

  • Developing on-body sensors, like on-skin sweat sensors, is challenging due to variable human skin characteristics, complicating in vivo testing and material development.
  • Current testing methods for wearables, cosmetics, and medical adhesives require expensive human trials with limited control over sweat mechanisms.

Purpose of the Study:

  • To introduce a versatile artificial skin platform that accurately replicates skin topography, active sweat pores, wetting behavior, and sweat rates.
  • To provide a tunable testbed for developing and validating wearable sensors and other skin-interfacing products.

Main Methods:

  • The artificial skin platform was engineered to simulate key skin properties, including surface texture and pore function.
  • The platform's sweat-generating capability was calibrated to cover a wide physiological range.

Main Results:

  • The artificial skin platform successfully recapitulates skin topography, active sweat pores, wetting behavior, and sweat rate.
  • It can generate sweat rates from 0.1 to 100 nL min⁻¹ pore⁻¹, encompassing the full spectrum of physiological sweat rates.
  • The platform is particularly suitable for testing sensors for individuals with lower sweat rates, such as sedentary persons.

Conclusions:

  • The developed artificial skin platform offers a realistic, adaptable, and stable testing solution for on-body sensors and related products.
  • It addresses the limitations of human subject testing by providing controlled and reproducible experimental conditions.
  • This innovation facilitates the development of advanced wearable technologies and skin-interfacing products, especially for niche applications like low-sweat-rate individuals.