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Updated: Aug 3, 2025

Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency
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Published on: June 10, 2018

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Induction and application of human naive pluripotency

Jianfeng Zhou1, Jindian Hu1, Yixuan Wang1

  • 1Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200120, China; Frontier Science Center for Stem Cell Research, Tongji University, Shanghai 200092, China.

Cell Reports
|April 12, 2023
PubMed
Summary

Researchers have developed new methods to generate human naive pluripotent stem cells in vitro. These cells offer insights into early development, X chromosome inactivation, and disease modeling.

Keywords:
CP: Stem cell researchblastoidsembryonic developmentembryonic stem cellshuman naive pluripotencyinduced pluripotent stem cells

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