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Using complete blood count-derived inflammatory markers to compare postoperative inflammation in dogs undergoing open
Lorena Espadas-González1, Jesús M Usón-Casaús1, Nieves Pastor-Sirvent1
1Department of Animal Medicine, University of Extremadura, Cáceres, Spain.
Background:
The inflammatory response triggered in dogs after laparoscopic ovariectomy (LapOV) or ovariectomy through mini-celiotomy (COV) has never been compared using the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and systemic inflammatory index (SII).
Methods:
Bitches underwent LapOV (n = 25) or COV (n = 25). NLR, PLR and SII were calculated 1 hour before ovariectomy (T0) and 2-3, 6-8 and 20-24 hours (T1-T3) after surgery.
Results:
Surgical time was longer in the LapOV group. Changes over time were observed in the NLR, PLR and SII in both groups (p < 0.001). PLR at baseline and T1 (p = 0.03 and 0.01) and NLR, PLR and SII at T2 (p = 0.01, 0.01 and 0.009) were higher in the LapOV group than in the COV group, but they did not differ at T3.
Limitations:
The overrepresentation of Greyhounds in the LapOV group and the short-term follow-up are the study's main limitations.
Conclusion:
Although an inflammatory peak was observed 6-8 hours after COV or LapOV, it was higher after the laparoscopy. However, there was no difference in the bitches' inflammatory status 24 hours after surgery.
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