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Helicobacter pylori Infection in Children: A Possible Reason for Headache?

Ancuta Lupu1, Cristina Gavrilovici1, Vasile Valeriu Lupu1

  • 1Pediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.

Diagnostics (Basel, Switzerland)
|April 13, 2023
PubMed

Insights

Helicobacter pylori (H. pylori) infection is significantly associated with headaches in children. This study highlights the importance of considering H. pylori in pediatric headache evaluations for prompt diagnosis and treatment.

Area of Science:

  • Pediatric Gastroenterology
  • Infectious Diseases
  • Neurology

Background:

  • The link between Helicobacter pylori (H. pylori) infection and headaches is debated, particularly in pediatric populations.
  • A clear association between H. pylori and headaches in children remains to be definitively established.
  • This study investigates the correlation in children from Northeast Romania.

Purpose of the Study:

  • To explore the relationship between H. pylori infection and the occurrence of headache or migraine in children.
  • To determine if H. pylori infection is a significant factor in pediatric headaches.

Main Methods:

  • A retrospective study design was employed.
  • Data from 1757 children hospitalized over 3 years in a pediatric gastroenterology department were analyzed.
  • The study focused on children with diagnosed H. pylori infection and those presenting with headache or migraine.

Main Results:

  • Out of 1757 children, 130 experienced headaches.
  • A significant correlation was found between H. pylori infection and headache in children (χ2; p < 0.01).
  • Approximately 41.5% (54 out of 130) of children with headaches were also infected with H. pylori.

Conclusions:

  • A significant association exists between H. pylori infection and headaches in the studied pediatric cohort.
  • Further research is warranted to fully understand this relationship.
  • Identifying H. pylori infection may be clinically important for the diagnosis and treatment of headaches in children.

Keywords:
Helicobacter pylorichildrenheadachemigraine

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