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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Proteomics01:33

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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
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Updated: Aug 3, 2025

Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
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Towards Precision Prognostication and Personalized Therapeutics through Proteomics.

Enrique Santamaría1

  • 1Clinical Neuroproteomics Unit, Navarrabiomed, Hospitalario Universitario de Navarra (HUN), Navarra Institute for Health Research, Universidad Pública de Navarra (UPNA), IdiSNA, Irunlarrea 3, 31008 Pamplona, Spain.

International Journal of Molecular Sciences
|April 13, 2023
PubMed
Summary

Next-generation proteomics enables biomedical proteome research to identify disease-specific protein expression profiles. This approach aids in understanding disease mechanisms and discovering potential biomarkers for early detection and targeted therapies.

Area of Science:

  • Biomedical research
  • Proteomics
  • Molecular biology

Background:

  • Next-generation proteomics technologies have advanced the field of biomedical research.
  • Understanding protein expression profiles is crucial for disease research.

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