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Mortality, Intensive Care Unit Admission, and Intubation among Hospitalized Patients with COVID-19: A One-Year

Khaled Al Oweidat1,2, Rasmieh Al-Amer3,4, Mohammad Y Saleh5

  • 1Department of Respiratory and Sleep Medicine, Faculty of Medicine, The University of Jordan, Amman 11942, Jordan.

Journal of Clinical Medicine
|April 13, 2023
PubMed

Insights

This study identified key factors predicting COVID-19 severity in Jordanian patients. Chronic kidney disease and low oxygen saturation were linked to higher mortality, informing risk stratification for severe COVID-19 outcomes.

Area of Science:

  • * Infectious Diseases
  • * Public Health
  • * Critical Care Medicine

Background:

  • * The COVID-19 pandemic presented significant challenges to healthcare systems globally.
  • * Understanding risk factors for severe COVID-19 outcomes is crucial for patient management and resource allocation.

Purpose of the Study:

  • * To identify factors associated with COVID-19 mortality.
  • * To determine predictors of intensive care unit (ICU) admission and invasive intubation.
  • * To analyze factors influencing length of hospital stay in Jordanian COVID-19 patients.

Main Methods:

  • * A retrospective study involving 745 COVID-19 patients admitted to Jordan University Hospital over one year.
  • * Data collection included demographics, comorbidities, clinical parameters, laboratory results, and outcomes (mortality, ICU admission, intubation).
  • * Statistical analysis was performed to identify significant associations between variables and outcomes.

Main Results:

  • * Overall mortality, ICU admission, and invasive intubation rates were 23.0%, 28.3%, and 10.8%, respectively.
  • * Mortality was associated with chronic kidney disease (CKD), elevated troponin, lactate dehydrogenase (LDH), and oxygen saturation <90%.
  • * ICU admission linked to heart failure and remdesivir use; invasive intubation associated with oxygen saturation <90% and gastrointestinal symptoms.

Conclusions:

  • * Specific clinical and laboratory parameters can predict COVID-19 severity and adverse outcomes.
  • * Identifying high-risk populations is essential for targeted interventions and improved patient care.
  • * Findings can inform future research on COVID-19 complications and risk stratification.

Keywords:
COVID-19Jordaninfectious diseasesintensive careintubationretrospective

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