Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Management of benzodiazepine dependence.

P Moodley, M Lader

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |April 26, 1986
    PubMed
    Summary

    Benzodiazepine dependence is common, with a withdrawal syndrome occurring even at therapeutic doses. Gradual outpatient tapering over 4-12 weeks is the recommended management strategy.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Wound documentation by doctors in academic emergency departments, Gauteng Province, South Africa.

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025
    Same author

    Depression: an individual-level early warning indicator of virologic failure in HIV patients in South Africa.

    Public health action·2024
    Same author

    Venous thromboembolic disease in adults admitted to hospital in a setting with a high burden of HIV and TB.

    African journal of thoracic and critical care medicine·2021
    Same author

    Protocol for a randomised feasibility study of Point-Of-care HIV viral load testing to Enhance Re-suppression in South Africa: the POwER study.

    BMJ open·2021
    Same author

    A packaged intervention to improve viral load monitoring within a deeply rural health district of South Africa.

    BMC infectious diseases·2020
    Same author

    Comparative analyses of published cost effectiveness models highlight critical considerations which are useful to inform development of new models.

    Journal of medical economics·2019

    Area of Science:

    • Pharmacology
    • Psychiatry
    • Clinical Medicine

    Background:

    • Benzodiazepine dependence affects many patients on therapeutic doses.
    • A distinct benzodiazepine withdrawal syndrome is well-documented.

    Purpose of the Study:

    • To outline the optimal management strategy for benzodiazepine dependence.
    • To review pharmacological and non-pharmacological interventions for withdrawal symptoms.

    Main Methods:

    • Review of existing literature on benzodiazepine dependence and withdrawal.
    • Analysis of treatment approaches including gradual dosage reduction and adjunct therapies.

    Main Results:

    • Gradual outpatient dosage reduction over 4-12 weeks is the preferred management.
    • Pharmacological adjuncts (e.g., propranolol) offer limited symptomatic relief.
    • Psychological and social support show moderate success.
    • No single intervention effectively manages the majority of withdrawal symptoms.

    Conclusions:

    • The most effective approach to benzodiazepine dependence is preventative prescribing.
    • Comprehensive management involves gradual tapering, symptomatic treatment, and support.
    • Careful initial prescribing is crucial to avoid dependence.

    Related Experiment Videos