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The Role of Gluten in Gastrointestinal Disorders: A Review
Sabrina Cenni1, Veronica Sesenna2, Giulia Boiardi2
1Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Abstract:
Gluten is only partially digested by intestinal enzymes and can generate peptides that can alter intestinal permeability, facilitating bacterial translocation, thus affecting the immune system. Few studies addressed the role of diet with gluten in the development of intestinal inflammation and in other gastrointestinal disorders. The aim of this narrative review was to analyse the role of gluten in several gastrointestinal diseases so as to give a useful overview of its effectiveness in the prevention and management of these disorders.
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