Ocular complications in live-related renal transplant recipients: A single-centre study

Fatema Ali Lanewala1, Akhtar Jamal Khan1

  • 1Department of Ophthalmology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan.

Insights

Renal transplantation can cause ocular complications, with cataracts being most common. This study in Pakistan also found a high prevalence of night blindness in transplant patients.

Area of Science:

  • Nephrology
  • Ophthalmology
  • Transplantation Medicine

Background:

  • Renal transplantation is the primary treatment for end-stage kidney failure.
  • Post-transplant challenges include primary disease, surgical factors, and immunosuppressive medications.
  • Steroids are known to cause ocular complications in transplant recipients globally.

Purpose of the Study:

  • To report the pattern of ocular complications in renal transplant recipients.
  • To analyze data from an ophthalmology clinic at a dialysis and transplant center in Karachi, Pakistan.
  • To compare findings with international studies and identify unique patterns in the Pakistani population.

Main Methods:

  • Retrospective case series design.
  • Data collected from patients undergoing renal transplant.
  • Analysis of ocular complications observed since the establishment of the ophthalmology clinic.

Main Results:

  • Cataract was the most frequent ocular complication observed.
  • The findings align with previous international studies on post-renal transplant ocular issues.
  • A notable finding was the high prevalence of night blindness in the Pakistani cohort.

Conclusions:

  • Cataract is a common ocular complication following renal transplantation.
  • The high incidence of night blindness in Pakistani renal transplant recipients warrants further prospective investigation.
  • Understanding these patterns can help improve post-transplant patient care and monitoring.

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
30
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
41
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
45
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
45
Renal Corpuscle01:20

Renal Corpuscle

The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
2.9K
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
45