A Cheap and Efficient Oxidant (n-Bu)4NNO3-Enabled C(sp2)- and C(sp3)-H Olefination at Room Temperature
Cheng-Hao Gu1, Zhen Zhang1, Shuo-Jie Shen1
1State Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 210009, China.
Abstract:
To further promote the widely practical application of C-H activation, developing green and mild reaction conditions has invariably been the objective of researchers, especially when it comes to remote C-H activation reactions. Herein, we report a new cheap and powerful (n-Bu)4NNO3 oxidant. This oxidant is efficient and universal for Pd(II)-catalyzed sp2 and sp3 C-H olefination and allows the reaction to be carried out at room temperature. Because of this, we attempted to make C-H functionalization more economical and environmentally benign.
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