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Published on: March 26, 2020
Retinal Vascular Oxygen Saturation in Adults With Anisometropia
Shanshan Ge1,2, Liang Yang3, Yuehua Zhou1,2
1Eye School of Chengdu University of TCM, Chengdu, Sichuan, China.
Purpose:
This study aimed to examine the differences of retinal oxygen saturation between the paired eyes in anisometropia and to further explore the relation between retinal oxygenation and myopia.
Methods:
This was an observational cross-sectional study, with 124 adults with anisometropia included. According to the interocular differences in spherical equivalent (SE), individuals with a difference ≥3.0 D belonged to the ΔSE ≥ 3.0 D group, and those with a difference ≥1.5 D and <3.0 D belonged to the ΔSE <3.0 D group. The ΔSE ≥ 3.0 D group contained 61, and the ΔSE < 3.0 D group contained 64. All were performed examinations of retinal oximetry, SE, axial length (AL), intraocular pressure, central corneal thickness and average keratometry.
Results:
The median SE and AL were -5.06 (-7.22 ∼ -3.41) D and 25.54 (24.73 ∼ 26.62) mm in the "ΔSE < 3 D" group and -4.25 (-6.88 ∼ -2.09) D and 25.52 (24.49 ∼ 26.45) mm in the other group. The retinal arterial oxygen saturation (SaO2) was 93.97% ± 1.26% in the less myopic eyes and 93.18% ± 1.53% (P < 0.001) in the more myopic eyes. In multivariate analyses, SE and AL were both significantly associated with the SaO2.
Conclusions:
The SaO2 between anisometropic myopic eyes was different, and it was associated with SE and AL.
Translational Relevance:
This study demonstrates a relationship between myopia and retinal vascular oxygenation through a novel retinal oximeter.
