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Updated: Aug 2, 2025

Minimally Invasive Embryo Transfer and Embryo Vitrification at the Optimal Embryo Stage in Rabbit Model
Published on: May 16, 2019
Assisted reproductive technologies at the nexus of fertility treatment and disease prevention
Mary Herbert1,2,3, Meenakshi Choudhary2, Deidre Zander-Fox4,5
1Biosciences Institute, Newcastle University, Newcastle upon Tyne NE1 4EP, UK.
Abstract:
Assisted reproductive technology (ART) refers to processing gametes in vitro and usually involves in vitro fertilization. Originally developed for the treatment of infertility, culture of human embryos in vitro also provides an opportunity to screen embryos for inherited genetic disorders of the nuclear and mitochondrial genomes. Progress in identifying causative genetic variants has massively increased the scope of preimplantation genetic testing in preventing genetic disorders. However, because ART procedures are not without risk of adverse maternal and child outcomes, careful consideration of the balance of risks and benefits is warranted. Further research on early human development will help to minimize risks while maximizing the benefits of ART.
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