Related Experiment Video
Updated: Aug 2, 2025

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
Published on: January 26, 2024
Hydration and clinical warning signs of dengue fever in primary care: An observational prospective study
O Besnard1, O Maillard2, J-M Franco3
1Université de La Réunion - UFR Santé - Département universitaire de médecine générale, Site de l'IES, CHU de La Réunion, Saint-Pierre, France.
Objectives:
Dengue fever is an arbovirosis expanding worldwide, for which hydration has been reported to reduce the risk of hospitalization. Our objective was to estimate the volume of hydration in Reunionese patients with dengue.
Methods:
A prospective observational study included patients presenting with a 'dengue-like' syndrome in ambulatory care. General practitioners recruited patients during consultation, and beverage consumption over the previous 24 hours was reported at two different times. Warning signs were defined according to the 2009 WHO guidelines.
Results:
GPs included 174 patients from April to July 2019. Average oral hydration volume was 1863 mL and 1944 mL, at the 1st and 2nd medical consultations, respectively. Water was the most wide consumed liquid. Drinking at least 5 glasses of liquid was significantly associated with fewer clinical warning signs at the 1st medical consultation (p = 0.044).
Conclusions:
Sufficient hydration volume could prevent dengue warning signs. Further studies with standardized measurement of hydration would be needed.
Related Concept Videos
Disorder of Water Balance
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Increased Body Temperature
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Hypertension III: Clinical Manifestations and Diagnostic Studies
Rheumatic Heart Disease IV: Nursing Management
Heart Failure III: Clinical Manifestations

