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Updated: Aug 11, 2026
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5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
[Oxygen regimen of rat kidneys in regeneration and carcinogenesis]
Voprosy Onkologii
|January 1, 1986
Abstract:
Oxygen tension in the kidneys in compensatory hyperplasia after nephrectomy and in renal carcinogenesis induced by nitrosodimethylamine was studied in 80 albino noninbred rats. Regeneration and malignant transformation were found to involve similar changes in oxygen conditions in rat's kidneys, viz. disturbances in the function of microvessels and decreased utilization of oxygen.
