Related Experiment Video
Updated: Aug 2, 2025

13:45
Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
10.0K
Cervical Syphilitic Lymphadenitis in a 29-Year-Old Female: A Case Report.
David D Bickford1, Peter Johnson1, Nupur Brahmbhatt1
1Internal Medicine, Medical College of Wisconsin, Milwaukee, USA.
Cureus
|April 14, 2023
Summary
Syphilis can rarely cause cervical lymphadenopathy, especially in individuals with HIV. This case report emphasizes considering syphilis in the differential diagnosis for enlarged lymph nodes, even when lymphoma is suspected.
Area of Science:
- Infectious Diseases
- Oncology
- Public Health
Background:
- Cervical lymphadenopathy, or enlarged lymph nodes in the neck, is a frequent clinical finding with diverse etiologies.
- Potential causes range from infections and inflammatory conditions to neoplastic processes.
- Syphilis, a complex sexually transmitted infection, can present with cervical lymphadenopathy, particularly in immunocompromised individuals.
Observation:
- A case report details a patient with throat pain, systemic symptoms, and cervical lymphadenopathy.
- The initial clinical presentation mimicked lymphoma.
- Diagnosis revealed syphilis of unknown duration as the underlying cause.
Findings:
- Syphilis is an uncommon but significant cause of cervical lymphadenopathy.
- HIV-positive individuals and those with a history of intravenous drug use are at increased risk.
- Thorough patient history is crucial for accurate diagnosis.
Implications:
- Clinicians should include syphilis in the differential diagnosis for cervical lymphadenitis.
- Early and accurate diagnosis of syphilis is essential for effective treatment.
- Raising awareness of syphilis as a cause of lymphadenopathy can improve patient outcomes.
Related Concept Videos
Sexually Transmitted Infections
374
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
374
Acute Pharyngitis
1.1K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
1.1K
Tonsillitis I: Introduction
389
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
389

