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Published on: November 28, 2010
Ovarian aspergilloma in an immunocompetent patient masquerading as ovarian neoplasm
Gyanendra Singh1, Anurag Singh1, Anuragani Verma1
1King George's Medical University, Lucknow, India.
Abstract:
Aspergillus is a ubiquitous fungus that can cause a variety of clinical syndromes. It can lead to a spectrum of clinical presentations depending upon the severity of the disease, degree of immune compromisation, nature and intensity of inflammatory host response. Ovarian aspergilloma is extremely unusual, only a few case reports have been described in the literature. Here, we report a case of ovarian aspergilloma which was masquerading as ovarian neoplasm on clinical examination and radiology. To the best of our knowledge, this is the first case report of isolated ovarian aspergillosis in an immunocompetent patient.
Insights
This case report details an extremely rare instance of ovarian aspergilloma, a fungal infection of the ovary, in an immunocompetent patient. The condition mimicked ovarian neoplasm on initial evaluation, highlighting a diagnostic challenge.
Area of Science:
- Mycology
- Infectious Diseases
- Gynecologic Oncology
Background:
- Aspergillus is a common fungus causing diverse clinical syndromes.
- Ovarian aspergilloma is exceptionally rare, with limited documented cases.
- Fungal infections can present varied clinical manifestations based on host immunity and disease severity.
Observation:
- A case of ovarian aspergilloma is presented.
- The patient was immunocompetent, making the diagnosis more unusual.
- Clinical examination and radiology suggested ovarian neoplasm.
Findings:
- This report describes the first known case of isolated ovarian aspergillosis in an immunocompetent individual.
- The fungal infection presented as a potential ovarian tumor.
- Diagnostic imaging findings mimicked those of a neoplastic process.
Implications:
- Highlights the importance of considering rare fungal infections in gynecologic diagnostics.
- Suggests that ovarian aspergilloma can present as a mimicker of ovarian cancer.
- Emphasizes the need for thorough investigation in suspected ovarian neoplasms, even in immunocompetent patients.

