Related Experiment Video

Updated: Aug 2, 2025

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.4K

Neurocognitive abilities in children affected by sleep breathing disorders. A systematic review and meta-analysis of

D Fantozzi1, T Doldo1, C Luzi1

  • 1Unit of Orthodontics, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

European Journal of Paediatric Dentistry
|April 14, 2023
PubMed

Insights

Children with sleep breathing disorders (SBD) show significant neurocognitive deficits compared to healthy peers. This systematic review quantifies these deficits across various cognitive domains, highlighting the impact of SBD on child development.

Area of Science:

  • Pediatric Sleep Medicine
  • Neuropsychology
  • Developmental Pediatrics

Background:

  • Sleep breathing disorders (SBD) are increasingly recognized to impact children's neurodevelopment.
  • Previous studies suggest neurocognitive and behavioral impairments in children with SBD.
  • Mouth breathing is a common symptom associated with SBD in pediatric populations.

Purpose of the Study:

  • To systematically review and quantify neurocognitive deficits in pediatric patients with SBD, specifically those exhibiting mouth breathing.
  • To synthesize findings from relevant case-control studies using meta-analysis.
  • To assess the impact of SBD on various cognitive domains in children.

Main Methods:

  • A comprehensive literature search was conducted across major databases (Medline, Scopus, Scileo, Cochrane Library) from 2000 to June 2022.
  • Studies comparing neurocognitive skills in children with SBD versus healthy controls were selected based on PRISMA protocol and predefined inclusion/exclusion criteria.
  • Weighted Mean Differences (95% Confidence Intervals) were calculated for Wechsler Intelligence Scale for Children (WISC) test results.

Main Results:

  • Children diagnosed with SBD demonstrated poorer performance across nearly all investigated cognitive domains when compared to healthy control groups.
  • The meta-analysis quantified significant deficits in various aspects of cognitive function.
  • WISC test results consistently showed lower scores in SBD-affected children.

Conclusions:

  • The findings confirm that SBD significantly impacts cognitive functioning in children.
  • These neurocognitive deficits span multiple domains, underscoring the importance of addressing SBD in pediatric care.
  • Early identification and management of SBD may be crucial for mitigating long-term cognitive consequences.
Abstract

More Related Videos

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

12.0K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

748

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
204
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.5K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
201
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
188
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
213
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
297