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Updated: Aug 2, 2025

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Three-Tesla magnetic resonance imaging of left ventricular volume and function in comparison with computed tomography
Fu-Qian Guo1, Bai-Lin Wu, Xiao-Wei Liu
1Department of Medical Imaging, The Second Hospital, Hebei Medical University, Shijiazhuang, Hebei Province, China.
Insights
3-Tesla MRI and 256-slice CT (MSCT) show strong correlation in assessing left ventricle function. MSCT may serve as a viable alternative to MRI for cardiac evaluations.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Medical Diagnostics
Background:
- Accurate assessment of left ventricular function is crucial for diagnosing and managing cardiovascular diseases.
- 3-Tesla magnetic resonance imaging (MRI) is a gold standard for cardiac function assessment.
- Computed tomography (CT) and echocardiography (ECHO) are alternative imaging modalities with varying accuracy.
Purpose of the Study:
- To investigate the correlation and agreement between 3-Tesla MRI and 256-slice multi-detector computed tomography (MSCT) in evaluating left ventricular parameters.
- To compare the diagnostic performance of MSCT and 2-dimensional echocardiography (ECHO) against 3-Tesla MRI.
- To determine if MSCT can be a potential alternative to MRI for left ventricular assessment.
Main Methods:
- Retrospective analysis of 40 patients who underwent cardiac MSCT, 3-Tesla MRI, and 2-dimensional ECHO within one week.
- Quantitative analysis of left ventricular end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF).
- Statistical comparison of parameters obtained from MSCT and ECHO against 3-Tesla MRI, including correlation and limits of agreement.
Main Results:
- MSCT demonstrated a highly significant correlation with 3-Tesla MRI for all evaluated left ventricular parameters.
- MSCT showed minor overestimation of ESV and underestimation of EF and SV compared to MRI, with high consistency (95% limits of agreement).
- 2-dimensional ECHO also correlated significantly with MRI but exhibited wider agreement limits and a slight underestimation of left ventricular function.
Conclusions:
- 256-slice MSCT exhibits a strong correlation and agreement with 3-Tesla MRI in assessing left ventricular volumes and function.
- MSCT demonstrates superior correlation and agreement compared to 2-dimensional ECHO when evaluated against 3-Tesla MRI.
- MSCT may serve as a valuable and potentially cost-effective alternative to 3-Tesla MRI for routine left ventricular assessments.
Abstract:
This study investigated the correlation between 3-Tesla magnetic resonance imaging (MRI) and 256 multiple-slice computed tomography (MSCT) or 2-dimensional echocardiography (ECHO) in evaluating left ventricle. Forty patients were retrospectively enrolled to undergo cardiac MSCT, 3-Tesla MRI and 2-dimensional ECHO within 1 week. The end-diastolic (EDV) and end-systolic volume (ESV), stroke volume (SV) and ejection fraction (EF) were analyzed and compared. MSCT was highly significantly correlated with MRI. Compared with MRI, MSCT slightly overestimated ESV for about 8.7 mL, but slightly underestimated EF and SV for about 6.8% and 5.8 mL, respectively. A high consistency existed between MSCT and MRI, with the 95% limit of agreement (-19.6, 25.4) mL for EDV, (-2.6,20.1) mL for ESV, (-28.3,16.6) mL for SV, and (-18.8%,5.1) % for EF. ECHO was also significantly correlated with MRI. The ECHO slightly underestimated the left ventricular function compared with MRI, with an underestimation of 9.4 mL for EDV, 3.5 mL for ESV, 5.8 mL for SV and 1.0% for EF. A wider agreement limit existed between MRI and ECHO. MSCT has a better correlation and agreement relationship with MRI parameters than 2-dimensional ECHO in assessing the left ventricle and may serve as a possible alternative to MRI.
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