Related Experiment Video
Updated: Jul 21, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Association Between Moderate Physical Activity Level and Subsequent Frailty Incidence Among Community-Dwelling Older
Wenjing Zhao1,2, Shigekazu Ukawa3, Sachiko Sasaki4
1School of Public Health and Emergency Management, Southern University of Science and Technology, Shenzhen,China.
Abstract:
Our study aimed to demonstrate the association between physical activity (PA) and frailty incidence among Japanese community-dwelling older adults with a narrow age range of 70-74 years. This study included 485 participants from the Japan Gerontological Evaluation Study. Frailty was assessed at baseline and 3 years later by using the Kaigo-Yobo Checklist. PA was assessed using the short-term International PA Questionnaire at baseline. Logistic regression was performed to calculate the odds ratio with 95% confidence intervals after adjusting for potential confounders. The associations of frailty scores with both PA volume and daily walking time presented a U-shaped curve, albeit only the latter was statistically significant. After adjusting for potential confounders, walking for 0.5-1 hr/day displayed a greater association with decreased frailty risk than higher levels of daily walking time. Further study is needed to cumulate the evidence that moderate PA levels may delay frailty incidence and improve the aging process.
Related Concept Videos
Pharmacodynamics in Geriatric Patients: Effects of Age
Development of Human Microbiota

