Squamous cell carcinoma of the stomach: report of three cases

Three primary tumors of the stomach diagnosed as pure squamous cell carcinoma were reexamined with newly prepared multiple sections. In each tumor histological studies revealed minute areas of adenocarcinoma in addition to large areas of squamous cell carcinoma. This finding suggests that some gastric squamous cell carcinomas may be adenosquamous carcinomas with a predominant squamous component. The pathogenesis of primary squamous cell carcinoma of the stomach is discussed with respect to our observations and with due reference to the literature. The aggressive behavior of this tumor is also given attention.