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Related Experiment Videos

Nonspecific jejunitis--a challenging problem in children.

A K Sharma, N S Shekhawat, S Behari

    The American Journal of Gastroenterology
    |June 1, 1986
    PubMed
    Summary
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    This study describes a rare, severe necrotizing jejunitis in young people, presenting with acute abdominal pain and bloody stools. The condition involves small bowel ischemia and has a high mortality rate.

    Area of Science:

    • Gastroenterology
    • Infectious Diseases
    • Pathology

    Background:

    • Acute necrotizing jejunitis is an uncommon enteric infection primarily affecting young individuals.
    • Characterized by severe abdominal pain, bilious vomiting, and bloody, foul-smelling stools.

    Purpose of the Study:

    • To describe the clinical presentation, pathological findings, and potential etiology of acute necrotizing jejunitis.
    • To highlight the severity, course, and outcomes of this rare condition.

    Main Methods:

    • Case series review
    • Clinical observation
    • Pathological examination of small bowel tissue

    Main Results:

    • Findings include varying degrees of ischemic changes in the small bowel, from mucosal ulceration to gangrene.

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  • The condition presents with acute onset of severe abdominal pain, vomiting, and bloody diarrhea.
  • Mortality rates approximate 40%, with significant morbidity lasting 2-3 weeks.

    • Conclusions:

    • The exact etiology remains unknown, with possible links to gram-negative bacilli toxins or localized allergic reactions.
    • The disease follows a progressive but self-limiting course.
    • Clinical presentation shares similarities with conditions like Darmbrand and Pig-bel.