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Discontinuation of Intravenous Catecholamine by Oral Ivabradine in a Patient with Decompensated Heart Failure with

Ryo Shibata1, Jinya Takahashi1, Hiromi Sato1

  • 1Department of Cardiovascular Medicine, Kurume University School of Medicine.

The Kurume Medical Journal
|April 16, 2023
PubMed

Insights

Ivabradine effectively manages heart failure with sinus tachycardia by lowering heart rate. A patient dependent on intravenous catecholamines was successfully weaned off using oral ivabradine.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Heart failure with sinus tachycardia is a serious condition.
  • Catecholamine dependence indicates severe cardiac dysfunction.

Observation:

  • A patient with New York Heart Association (NYHA) class IV heart failure, reduced ejection fraction (LVEF) of 18%, and low cardiac output presented with catecholamine dependence.
  • Intravenous catecholamine administration was required to maintain cardiac function.

Findings:

  • Oral administration of ivabradine enabled the discontinuation of intravenous catecholamines.
  • Ivabradine reduced heart rate without negatively impacting left ventricular systolic function or blood pressure.

Implications:

  • Ivabradine offers a potential therapeutic option for managing severe, catecholamine-dependent heart failure.
  • This case highlights ivabradine's efficacy in patients with low cardiac output and high heart rates.

Keywords:
ivabradinelow cardiac outputsevere heart failure

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