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Mortality in a swiftly repurposed hospital in northeast Brazil during the first and second COVID-19 waves: A

Ana Paula M Porto1, José Xavier Neto1,2, Francisco Jadson Franco Moreira1

  • 1Escola de Saúde Pública do Estado do Ceará Paulo Marcelo Martins Rodrigues, Fortaleza, Ceará, Brazil.

IJID Regions
|April 17, 2023
PubMed

Insights

This study evaluated a repurposed hospital during COVID-19 waves. In-hospital mortality decreased from 48.8% in wave one to 36.2% in wave two, despite high mortality for ventilated patients.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Hospital Management

Background:

  • The COVID-19 pandemic necessitated rapid repurposing of healthcare facilities.
  • A private hospital in Ceará, Brazil, was transformed into a public tertiary COVID-19 center.
  • The study examines the hospital's performance during the first and second waves of the pandemic.

Purpose of the Study:

  • To evaluate the performance of a repurposed hospital during the COVID-19 pandemic.
  • To assess improvements in patient outcomes between the first and second waves.
  • To identify factors associated with in-hospital mortality.

Main Methods:

  • Retrospective cohort study of 2492 COVID-19 patients.
  • Data collected via a dedicated web platform (ResCOVID).
  • Poisson regression used to analyze factors associated with in-hospital mortality.

Main Results:

  • Significant differences in demographics and clinical features between the two waves.
  • In-hospital mortality decreased from 48.8% in the first wave to 36.2% in the second wave.
  • Invasive mechanical ventilation strongly associated with increased mortality in both waves (RR 4.28 and 12.94).

Conclusions:

  • The repurposed hospital was crucial for Ceará's public health response to COVID-19.
  • The facility effectively managed moderate-to-severe cases, reducing strain on other services.
  • While mortality for intubated patients remained high, overall in-hospital mortality significantly decreased in the second wave.
Abstract

Keywords:
BrazilCOVID-19MortalityPublic health

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